Objective : To demonstrate the flexibility, adaptability and efficacy of endoscopic endonasal removal of in­ferior half of the middle turbinate in a cadaveric study and in surgery for the treatment of different sphenoid sinus and skull base lesions.
Study Design: prospective study Methods :    Anatomic Cadaveric Study : Five adult cadaveric heads were studied. Six nostrils of 3 cadav­ers were studied endoscopically after removal of lower half of the middle turbinate. Two adult cadaveric heads underwent bilateral paraseptal sagittal sections and studied after removal of the lower half of the middle turbinate.
Surgical study: Sixty five patient* with different sphenoid sinus and skui: base related lesions underwent sur­gery through this approach.
Results:            
In anatomic cadaveric study : This approach offered more surgical space, less restricted tubular vision and offered wider anatomic panoram­ic orientation with 0° and angled en-doscopes.
In the surgical group : there was no major intra- or postoperative com­plications. The approach allowed bet­ter exposure, accessibility of the le­sion and subsequently good hemostasis, tumor resection