Background: In cirrhotic patients, the presence of esophageal varices could have a mechanical effect on the motility of the esophagus and the in­tegrity of the lower esophageal sphi­ncter. Endoscopic management of esophageal varices, either by sclero-therapy or band ligation, was suggest­ed to have an effect on esophageal motility and lower sphincter pressure, due to damage of intima, mucosa and submucosa of veins. The aim of this study is 1o compare between sclero-therapy and band ligation as an effect on esophageal motility and lower sphincter pressure after eradication of varices.
Methods : ninety six patients with upper gastrointestinal bleeding from
esophageal varices (proved endo-scopically) were included in this study. They were divided into two groups: Group I ; included 46 pa­tients, received sclerotherapy and group II, included 50 patients received band ligation They were followed every two weeks endoscopically, till complete eradication of varices. Sta­tionary esophageal manometry was done to all patients before endoscopic treatment and after complete eradica­tion of varices.
Results : No significant difference between both groups as regard age, gender, etiology and severity of liver disease, laboratory findings, grading and number of varices, In sclerothera­py group there is high significant de­crease in lower sphincter pressure