This study was conducted on 40 ASA physical status I-11 outpatients who were scheduled for unilateral ESWL to evaluate the safety and efficacy of ketamine versus fentanyl when infused in combination with mid-azolam for sedation and analgesia. Patients were randomly allocated into two equal groups according to the study drug used ketamine group and fentanyl group. Midazolam 1-3 mg was given to all patients IV to relieve anxiety. Heart rate, systolic and dia-stolic blood pressure, respiratory rate and oxygen saturation were recorded every 5 min during ESWL procedure. Involuntary movements, respiratory upsets, episodes of desaturation, nausea / vomiting and complaints of pain were also recorded. Although both drug regimens allowed the maximal number of shock waves and energy levels, ketamine infusion provid-
ed superior intraoperative cardiores-piratory stability. However it was associated with more disruptive movements during the procedure and longer recovery times. Incidence of-common postoperative side effects (nausea, vomiting, dizziness, confusion) did not differ significantly between the two groups. From the results of the study we can conclude that lithotripsy can be satisfactorily performed by employing ketamine infusion in combination with mrdazolam for sedation and analgesia.
This study was conducted on 40 ASA physical status I-11 outpatients who were scheduled for unilateral ESWL to evaluate the safety and efficacy of ketamine versus fentanyl when infused in combination with mid-azolam for sedation and analgesia. Patients were randomly allocated into two equal groups according to the study drug used ketamine group and fentanyl group. Midazolam 1-3 mg was given to all patients IV to relieve anxiety. Heart rate, systolic and dia-stolic blood pressure, respiratory rate and oxygen saturation were recorded every 5 min during ESWL procedure. Involuntary movements, respiratory upsets, episodes of desaturation, nausea / vomiting and complaints of pain were also recorded. Although both drug regimens allowed the maximal number of shock waves and energy levels, ketamine infusion provid-
ed superior intraoperative cardiores-piratory stability. However it was associated with more disruptive movements during the procedure and longer recovery times. Incidence of-common postoperative side effects (nausea, vomiting, dizziness, confusion) did not differ significantly between the two groups. From the results of the study we can conclude that lithotripsy can be satisfactorily performed by employing ketamine infusion in combination with mrdazolam for sedation and analgesia.