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207624

HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS

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Last updated: 26 Dec 2024

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Abstract

Chemical composition of milk thistle seed flour )MTSF) and turmeric (T) were investigated, for milk thistle seed flour,  moisture (8.0%), protein (13.0 %), carbohydrates (27.55%), crude lipid (15.0%), ash (10.45%), and crude fiber (26.0%), while turmeric has moisture (8.1%) ,  protein (9.3 %), carbohydrates (57%), crude lipid (17.0%), ash (6.0%) and crude fiber (2.6%). For total phenol, the highest value in turmeric (11.57mg GAE/g) while milk thistle seed flour (3.39 mg GAE/g)) also total flavonoid for turmeric (4.9mg) while and in milk thistle seed flour (2.34mg). DPPH for milk thistle recorded the highest percent of (FRSA) 98.5 % and turmeric recorded lowest present 82.2% in concentration 100 µg/ml. Reducing power for milk thistle recorded 0.651 but turmeric (T) recorded 0.502 in concentration 100 µg/ml . The identification of phenolic compounds for plant extracts were investigated by HPLC ,the highest content in milk thistle seed flour (MTSF) was Benzoic acid (103.33 ppm) while the lowest content was Caffeine(1.07 ppm) but in turmeric(T) the highest content was Benzoic acid (208.41 ppm), while the lowest content was quercitin (3.08 ppm).The level of plasma aspartate aminotransferase (AST) , alanine aminotransferase (ALT) , alkaline phosphatase (ALP) , total bilirubin , total protein and albumin and plasma antioxidant state SOD , CAT, GPx and MDA were determined to assay hepatotoxicity.

DOI

10.21608/mjab.2021.207624

Keywords

Milk thistle seed flour, disorder, Biochemical analyss

Authors

First Name

F. M.

Last Name

El-Shouny

MiddleName

-

Affiliation

Biochemistry- Dep., Faculty of Agricultural, Menoufia University

Email

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City

-

Orcid

-

First Name

S. K.

Last Name

El-Kadousy

MiddleName

-

Affiliation

Biochemistry- Dep., Faculty of Agricultural, Menoufia University

Email

-

City

-

Orcid

-

First Name

S. M.

Last Name

El-Gawad

MiddleName

-

Affiliation

Biochemistry- Dep., Faculty of Agricultural, Menoufia University

Email

-

City

-

Orcid

-

First Name

Kh. A.

Last Name

El-Khalwy

MiddleName

-

Affiliation

Biochemistry- Dep., Faculty of Agricultural, Menoufia University

Email

-

City

-

Orcid

-

Volume

6

Article Issue

6

Related Issue

29218

Issue Date

2021-11-01

Receive Date

2021-12-04

Publish Date

2021-11-01

Page Start

57

Page End

69

Print ISSN

2357-0768

Online ISSN

2735-3532

Article File

MJAB_Volume 6_Issue 6_Pages 57-69.pdf

PDF . 615.9kB

Link

https://mjab.journals.ekb.eg/article_207624.html

Detail API

https://mjab.journals.ekb.eg/service?article_code=207624

Order

3

Type

original papers

Type Code

1,460

Publication Type

Journal

Publication Title

Menoufia Journal of Agricultural Biotechnology

Publication Link

https://mjab.journals.ekb.eg/

MainTitle

HEPATOPROTECTIVE EFFECTS OF TURMERIC AND MILK THISTLE SEED FLOUR AGAINST ETHANOL LIVER DAMAGE IN WISTER RATS

Details

Type

Article

Created At

23 Jan 2023