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176603

BIOCHEMICAL STUDIES ON MORINGA SEEDS

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Last updated: 04 Jan 2025

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Abstract

The present work aims to study the potential effect of Moringa Oleiferato (MO) seed oil and seed ethanol extract to give more protection against hyperlipidemia . Thirty male albino rats were used over 30 days period. The animals were divided into (5) groups, wherein groups number (1) represent control which were fed basal diet, while group number (2) was received high fat diet to serve as hyperlipidemic group. Other three groups allowed to feed high fat diet supplemented with seed oil , seed ethanol extract and atrovastatin, group number (3) treated simultaneously with moringa seed oil, fourth group treated with moringa seed ethanol extract while the last group treated with atrovastatin.  At the end of the experimental period, blood samples were collected to determine lipid profile and determine the kidney functions include urea nitrogen and creatinine. Also liver was removed surgically for histopathological observation. From the obtained results we concluded that group of rats fed on high fat diet were considered as a major risk factor for hyperlipidemia disease. Our results could be summarized that moringa seed oil and moringa seed ethanol extract were considered the best for causing a reduction of TC, TG and LDL . Also, kidney function has been improved and there were significant reduction urea and creatinine than that of positive control group. It could be concluded that moringa seed oil and moringa seed ethanol extract under study are useful for the treatment of hyperlipidemia.

DOI

10.21608/mjab.2016.176603

Keywords

Moringa, hyperlipidemia, Liver, oil

Authors

First Name

M. A.

Last Name

Hammam

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Affiliation

Prof. of Agricultural Biochemistry, Fac. of Agric., Menoufia Univ.

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First Name

G. A.

Last Name

Khalil

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Affiliation

Associate Prof. of Agricultural Biochemistry, Fac. of Agric., Menoufia Univ.

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Orcid

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First Name

S.M.

Last Name

Abd ElGawad

MiddleName

-

Affiliation

Associate Prof. of Agricultural Biochemistry, Fac. of Agric., Menoufia Univ.

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Volume

1

Article Issue

1

Related Issue

25581

Issue Date

2016-08-01

Receive Date

2021-06-09

Publish Date

2016-08-01

Page Start

39

Page End

40

Print ISSN

2357-0768

Online ISSN

2735-3532

Article File

MJAB_Volume 1_Issue 1_Pages 39-40.pdf

PDF . 185.3kB

Link

https://mjab.journals.ekb.eg/article_176603.html

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https://mjab.journals.ekb.eg/service?article_code=176603

Order

4

Type

original papers

Type Code

1,460

Publication Type

Journal

Publication Title

Menoufia Journal of Agricultural Biotechnology

Publication Link

https://mjab.journals.ekb.eg/

MainTitle

BIOCHEMICAL STUDIES ON MORINGA SEEDS

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Article

Created At

23 Jan 2023