169571

BIOCHEMICAL STUDIES ON SOME NANOTECHNOLOGY APPLICATIONS

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Last updated: 04 Jan 2025

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Abstract

Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications.             our study aims to introduce a simple, rapid and economical route to synthesize silver nanoparticles (AgNPs) using aqueous and methanolic extracts from two medicinal plants; ginger and lemon grass as reducing and stabilizing agent, AgNPs synthesis was inferred by the change of color from yellow to brown. The size, morphology and stability of AgNPs depend on the active ingredients in the extracts. AgNPs size and morphology were characterized using Ultraviolet-visible (UV-Vis) spectrum of synthesized AgNPs shows a peak from 410-425 nm approximately. and transmission electron microscopy (TEM) analysis indicated spherical shape of nanoparticles with average size of 13.0 - 35 nm. We investigate the antioxidant effect of (AgNPs) synthesized from aqueous and methanolic extracts in both in vitro and in vivo, and we can conclude that, silver nanoparticles recorded the most potent in vitro  and in vivo antioxidant effect and can   protect liver, kidney and heart of rats against oxidative stress caused by H2O2 (0.5 % in drinking water), also have antibacterial effect against some human pathogenic bacteria.

DOI

10.21608/mjab.2020.169571

Keywords

Silver nanoparticles (AgNPs), Green synthesis, Ginger, Lemon grass, Antioxidant activity

Authors

First Name

M. A.

Last Name

Hammam

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Affiliation

Prof. of Agric Biochemistry, Fac. of Agric., Menoufia Univ.

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First Name

S. M. Abd

Last Name

ElGawad

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Affiliation

Prof. of Agric Biochemistry, Fac. of Agric., Menoufia Univ.

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First Name

Manal K. I. El-

Last Name

Bisi

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Affiliation

Prof. of Textile Chemistry and Technology, National Research Center, Dokki, Cairo.

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First Name

G. A.

Last Name

Khalil

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Affiliation

Associate prof. of Agric Biochemistry, Fac. of Agric., Menoufia Univ.

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Volume

5

Article Issue

1

Related Issue

24738

Issue Date

2020-02-01

Receive Date

2021-05-08

Publish Date

2020-02-01

Page Start

41

Page End

42

Print ISSN

2357-0768

Online ISSN

2735-3532

Link

https://mjab.journals.ekb.eg/article_169571.html

Detail API

https://mjab.journals.ekb.eg/service?article_code=169571

Order

4

Type

original papers

Type Code

1,460

Publication Type

Journal

Publication Title

Menoufia Journal of Agricultural Biotechnology

Publication Link

https://mjab.journals.ekb.eg/

MainTitle

BIOCHEMICAL STUDIES ON SOME NANOTECHNOLOGY APPLICATIONS

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Article

Created At

23 Jan 2023