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169570

HEPATOPROTECTIVE EFFECT AND ANTIOXIDANT ACTIVITY OF SILVER NANOPARTICLES BIOSYNTHESIS FROM CYMBOPOGAN CITRATUS (LEMONGRASS)

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Last updated: 04 Jan 2025

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Abstract

Green synthesis of silver nanoparticles (AgNPs) is non-toxic, rabid and eco-friendly than commonly used physicochemical methods. This study focuses on synthesis, characterization, hepatoprotective effect and antioxidant activity of AgNPs synthesizes from Cymbopogan Citratus (Lemongrass). Silver nanoparticles were formed within 30 minutes by heating to 80oC magnetic stirrer using aqueous solution of AgNO3 (0.1 N) with fresh leaves methanolic extract of Cymbopogan Citratus. The synthesized silver nanoparticles were characterized by using UV-visible spectrophotometer analysis and transmission electron microscope (TEM). The antioxidant activity of nanoparticles were determined in vitro by reducing power, total antioxidant capacity and free radical scavenging activity by (DPPH). and experimental study was designed to evaluate the antioxidant activity and hepatoprotective effect of silver nanoparticeles, methanolic extract and essential oil comparing with vitamin E. Results: (UV-Vis) spectrum of synthesized AgNPs shows a peak at 412 nm and the size of silver nanaoparticels was 13.5 nm by (TEM). Silver nanoparticles showed potent hepatoprotective effect and antioxidant activity in both in vitro and in vivo methods.  

DOI

10.21608/mjab.2020.169570

Keywords

Silver nanoparticles (AgNPs), Green synthesis, Lemon grass, Antioxidant activity, DPPH (2, 2-diphenyl -1- pricrylhydrazyl)

Authors

First Name

M. A.

Last Name

Hammam

MiddleName

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Affiliation

Department of Biochemistry Faculty of Agricultural Menofia Univeristy shibin El-Kom, Egypt

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Orcid

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First Name

G. A.

Last Name

Khalil

MiddleName

-

Affiliation

Department of Biochemistry Faculty of Agricultural Menofia Univeristy shibin El-Kom, Egypt

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City

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Orcid

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First Name

S. M. Abd

Last Name

ElGawad

MiddleName

-

Affiliation

Department of Biochemistry Faculty of Agricultural Menofia Univeristy shibin El-Kom, Egypt

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City

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Orcid

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First Name

Manal K. I. El-

Last Name

Bisi

MiddleName

-

Affiliation

Prof. Doctor at chemical and technology of textile National research center

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City

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Orcid

-

First Name

I. A. A.

Last Name

Mohamed

MiddleName

-

Affiliation

Ministry of Health and Population, Egypt.

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Volume

5

Article Issue

1

Related Issue

24738

Issue Date

2020-02-01

Receive Date

2021-05-08

Publish Date

2020-02-01

Page Start

11

Page End

22

Print ISSN

2357-0768

Online ISSN

2735-3532

Article File

MJAB_Volume 5_Issue 1_Pages 11-22.pdf

PDF . 1.1MB

Link

https://mjab.journals.ekb.eg/article_169570.html

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https://mjab.journals.ekb.eg/service?article_code=169570

Order

3

Type

original papers

Type Code

1,460

Publication Type

Journal

Publication Title

Menoufia Journal of Agricultural Biotechnology

Publication Link

https://mjab.journals.ekb.eg/

MainTitle

HEPATOPROTECTIVE EFFECT AND ANTIOXIDANT ACTIVITY OF SILVER NANOPARTICLES BIOSYNTHESIS FROM CYMBOPOGAN CITRATUS (LEMONGRASS)

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Type

Article

Created At

23 Jan 2023