Corrugated steel-plate girders (GCWs) are nowadays used as structural elements in many applications for their high strength against shear buckling, otherwise cutouts are always provided in these plate elements to enable inspection and servicing. This study presents an experimental and analytical study for investigating the behavior of girders with corrugated webs (GCWs) having cutouts under shear loading. The experimental program was conducted on three full-scale plate girders, which have been tested under central load at mid-span. The theoretical analysis was conducted using ANSYS V20 to perform a nonlinear technique for the determination of the ultimate shear capacity of the tested girders. Finally, experimental, and finite element model were used to define the ratio of decreasing in carrying capacity for corrugated web, having cutout under shear loading. As expected from the ultimate strength, failure mechanism, and load-deflection curves that results of ultimate load carrying capacity decreased with the appearance of one or more cut-outs.