Riverbank filtration (RBF) is a process in which river water is induced to flow through riverbed soils to pumping wells located on the banks. During this passage through the riverbed and aquifer, dissolved and suspended contaminants as well as pathogens are removed. In Upper Egypt, there is interesting in implementation of RBF because it has the potential to replace the current bad quality groundwater wells. In this study, a pilot studied site consisting of three handpumps installed about 8 m from a main canal was monitored. These handpumps are used to supply potable water for private houses, Qena Governorate, Upper Egypt. Water samples from these handpumps, main canal, and municipal groundwater wells were examined. Quality measurements were carried out. The results of these bank handpumps were compared with those of canal and municipal groundwater wells. Phiso-chemical quality of handpumps water is acceptable for drinking. There is a caution about the microbial quality of produced water. The cost of applying RBF technique is less than traditional surface water or groundwater treatment plant. Results of this pilot-scale site showed the effectiveness of RBF as a suitable method in Upper Egypt with low cost.