Sepsis is a leading cause of morbidity and mortality in critical care patients , Fluid therapy represents one of the cornerstones of resuscitation treatments in sepsis, in order to increase oxygen delivery and hemodynamics during circulatory failure.
The SOFA score is one of the best validated disease-oriented end points available for critically ill patients and is correlated with mortality risk Se
We hypothesise that the administration of 5% Dextrose for fluid maintenance and drug infusion in critically ill septic shock patients will lead to a decrease in SOFA score when compared to administration of 0.9% NaCl.
AIM OF THE WORK
The aim of this study is to compare the efficacy of maintenance fluid therapy by 5% dextrose compared to 0.9% NaCl in reducing organ dysfunction in critically ill sepsis patients.
Patients
Among patients crtical care units, adult patients (aged 18 years or older) with septic shock were included.

Initial resuscitation in ER was done according to surviving sepsis campaign then patients were randomized one of two arms: