MRI is an important diagnostic tool used in MS diagnosis that can help fulfill the criteria of dissemination in space and time guided by the Mc Donalds criteria. Despite high sensitivity and specificity to Mc Donalds criteria, there are still issues of delayed diagnosis and misdiagnosis. As a result the Magnetic Resonance Imaging in MS (MAGNIMS) group and the Consortium of MS Centers (CMSC) have called for more studies into more MRI specific diagnostic biomarkers for MS such as the central vein sign and the paramagnetic rim sign. SWI sequence has the ability to visualize these new biomarkers which can potentially allow for an earlier and more accurate diagnosis of MS as well as provide additional information regarding the age and the presence of chronic
AIM OF WORK:
The aim of this study was to evaluate the added value of SWI in evaluation of patients with Multiple Sclerosis.
PATIENTS AND METHODS:
Thirty clinically definite MS patients according to McDonalds criteria underwent clinical brain MRI scans including: T1W, T2W, FLAIR, DWI, SWI and 3D FLAIR. Fourteen patients underwent contrast enhanced MRI studies.18 Patients were scanned on a 1.5T and 12 patients were scanned on 3T MRI at Radiodiagnosis Department, Faculty of Medicine, Alexandria University.