Adaptive support ventilation (ASV) is a closed loop mode that automatically switch from mandatory pressure control ventilation to pressure-control synchronized intermittent mandatory ventilation or pressure support ventilation, depending on the patient's lung statusthereby reducing the work of breathing. We targeted to observe the patients with moderate acute respiratory distress syndrome (ARDS) ventilated with ASV as a sole mode of mechanical ventilation, duration of mechanical ventilation, weaning duration and length of Intensive care unit (ICU) stay.
AIM OF THE WORK
The aim of this study was to compare between ASV and Conventional ventilation as a full ventilation mode in ARDS patients according to total days of mechanical ventilation and weaning success rates.
PATIENTS AND METHODS:
The study included 68 adult male and female patients with moderate ARDS who were admitted to the Alexandria Main University Hospital's Critical Care Department.
This is a single-center, prospective cohort study.
The patients will be randomly enrolled into one of two protocols:
Group A: patients will be ventilated using ASV in the following steps:
1. Setting the ideal body weight in Kg.
2. Seting the physiological Min Vol as being equal to 0.1 L/kg of ideal body weight (IBW).
3. Min Vol was started at 100% and was adjusted according to the Paco2 levels for passive patients or patient's RR for spontaneously breathing patients.