Beta
226728

THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT

Article

Last updated: 26 Dec 2024

Subjects

-

Tags

-

Abstract

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In this new definition the concept of non-homeostatic host response to infection is strongly stressed while the SIRS criteria have been removed.
However, the diagnosis of sepsis and evaluation of its severity is complicated by the highly variable and non-specific nature of the signs and symptoms of sepsis. From this point biomarkers have an important place in the process of early diagnosis and stratification of the severity of sepsis and can differentiate between infectious and non-infectious causes of systemic inflammatory response
The intensive care infection score (ICIS) a novel score for prediction of sepsis comprised five blood-cell derived parameters that characterize the early innate immune response which are: The mean fluorescence intensity of segmented neutrophils (SNFI), difference in hemoglobin concentration between newly formed and mature red blood cells (dCHC), total segmented neutrophil count (SN), antibody secreting lymphocyte count (ASL) and immature granulocyte count (IG).
A high ICIS increases the likelihood of infection when suspected and a low ICIS decreases it. This may help the clinician in ordering extra tests or starting empirical antibiotics.

DOI

10.21608/alexpo.2022.128010.1387

Keywords

Sepsis, The intensive care infection score (ICIS), PROCALCITONIN LEVEL AND CRP

Authors

First Name

Tayseer

Last Name

Zaytoun

MiddleName

M.

Affiliation

Critical Care Medicine Department, Faculty of Medicine, University of Alexandria.

Email

tayserzaytoun.icu@gmail.com

City

-

Orcid

-

First Name

Osama

Last Name

Hassan

MiddleName

S.

Affiliation

Critical Care Medicine Department, Faculty of Medicine, University of Alexandria.

Email

drosamasaed@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Nawar

MiddleName

Osama

Affiliation

Critical Care Medicine Department, Faculty of Medicine, University of Alexandria.

Email

isabellorino@gmail.com

City

-

Orcid

-

Volume

4

Article Issue

1

Related Issue

29866

Issue Date

2022-03-01

Receive Date

2022-03-17

Publish Date

2022-03-01

Page Start

51

Page End

52

Online ISSN

2682-2636

Link

https://alexpos.journals.ekb.eg/article_226728.html

Detail API

https://alexpos.journals.ekb.eg/service?article_code=226728

Order

3

Type

Preliminary preprint short reports of original research

Type Code

1,426

Publication Type

Journal

Publication Title

ALEXMED ePosters

Publication Link

https://alexpos.journals.ekb.eg/

MainTitle

THE DIAGNOSTIC VALUE OF INTENSIVE CARE INFECTION SCORE IN COMPARISON TO PROCALCITONIN LEVEL AND CRP IN SEPTIC ICU PATIENT

Details

Type

Article

Created At

23 Jan 2023