Diaphragmatic assessment in Chronic Obstructive Pulmonary Disease (COPD) has a major clinical relevance as COPD patients have a risk of diaphragmatic dysfunction which may affect ventilatory management during acute exacerbation.
Ultrasonography is a reasonable non -invasive method for diaphragmatic assessment in acute exacerbation of COPD patients, thus the purpose of the study was to investigate impact of ultrasound assessed diaphragmatic impairment on non - invasive mechanical ventilation (NIMV) outcome in acute exacerbation.
Aim of the work:
Was to determine the ability of ultrasound assessed diaphragmatic impairment to predict NIMV failure and the need of invasive mechanical ventilation in acute exacerbation of COPD.
Subjects and Methods:
Subjects:
This study was performed on seventy-five patients with acute exacerbation COPD who admitted to the critical care department units and eligible for non-invasive mechanical ventilation (NIMV)
Methods:
An observational prospective study was conducted:
The following data were recorded on admission: patient's criteria, patient's clinical parameters, laboratory parameters and arterial blood gases on admission and after NIMV.
Diaphragmatic thickness was measured on both sides before NIMV and diaphragmatic Thickness fraction was calculated, the Patients enrolled in the study were followed up for NIMV outcome, ICU stay and mortality.
Patients were categorized into two groups according to their primary outcome (NIMV success).