Periorbital hyperpigmentation (POH) is a common problem encountered in practice. It presents as bilateral round or semicircular homogenous macules of brown or dark brown hue in the periorbital region.
The causative factors include genetic or heredity, excessive pigmentation, postinflammatory hyperpigmentation secondary to atopic and allergic contact dermatitis, periorbital edema, excessive vascularity, and shadowing due to skin laxity and tear trough associated with aging.
Periorbital wrinkles are caused by the muscular activity linked to facial mimicry, together with photoaging, cutaneous sagging and volume loss caused by osseous and subcutaneous tissue reabsorption and are considered an important component of facial aging.
Platelet-rich plasma (PRP) is an easy, efficient, and minimally invasive way to obtain a natural concentration of autologous growth factors (GFs). Production of PRP consists of centrifugation of autologous blood leading to separation and extraction of the plasma and buffy coat portion of the blood that contain the highest concentrations of platelets.