Endometrial carcinoma is the sixth most common cancer in women worldwide, contributing to 4.5 % of the total number of new cases diagnosed in 2020. In USA, uterine cancer is the fourth cancer among women, representing 7% of all new cancer cases after breast, lung and colorectal cancers.
Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed estrogen therapy, early menarche, late menopause, tamoxifen therapy, nulliparity, failure to ovulate and polycystic ovary syndrome. Additional risk factors are increasing age, obesity, hypertension, diabetes mellitus, Lynch syndrome.
The most common presentation for endometrial cancer is postmenopausal bleeding. Most cases presented at early stage (I/II). Transvaginal ultrasonography and endometrial biopsy are recommended as the initial study. Further imaging method like CT plays an important role for advanced stages.
Aim of the work
The aim of the work was to evaluate and analyze the experience of the Gynecological Oncology Unit in El Shatby Maternity University Hospital with endometrial cancer patients as regard demographic data, clinical picture, modalities of diagnosis, management and pathology.