This experiment was carried out during the two successive seasons 2020 and 2021 on Flame Seedless grapevines grown in sandy soil under drip irrigation system at EL-Tahrir, El Beheira Governorate. The aim of this study was to save irrigation water without any reduction of water use efficiency, growth and productivity of Flame Seedless grapevine under desert condition. The experiment design was arranged in a split- plot with three replications. The main plots were divided into three drip irrigation systems, i.e. surface drip irrigation, subsurface drip irrigation and Oscop drip irrigation either a solely form alone or in combined with three doses of polymer i.e. zero, 25 and 50g. The sub-plots were allocated to three irrigation levels (100%, 75% and 50% of water requirements). The obtained results cleared that: Oscop drip irrigation with 50g of polymer under 75% of water requirements resulted the best vegetative growth, cluster weigh, total yield, cluster length and width, berry dimensions, weight and volume  of 100 berries, soluble solids content (SSC) and sugar contents in berries Juice. Also, Oscop drip irrigation with 50g of polymer under 75% of water requirements improve water use efficiency. On the other side, Oscop drip irrigation with 50g of polymer under 75% of water requirements gave the lowest total acidity in both seasons.