This experiment was carried out during the two successive seasons 2020 and 2021 on Flame Seedless grapevines grown in sandy soil under drip irrigation system at EL-Tahrir, El Beheira Governorate. The aim of this research was to save irrigation water without any reduction of water use efficiency, yield and fruit quality of Flame Seedless grapevines under desert condition. The experiment design was arranged in a split- plot with three replications. The main plots were divided into three drip irrigation systems, i.e. surface drip irrigation, subsurface drip irrigation and Oscop drip irrigation either a solely form alone or in combined with three doses of polymer i.e. zero, 25 and 50g. The sub-plots were allocated to three irrigation levels (100%, 75% and 50% of water requirements). The obtained results cleared that Oscop drip irrigation with 50g of polymer under 75% of water requirements resulted in the best results in terms of increasing the yield and its components and ensuring the best physical and chemical properties of clusters and berries as well as improving the water use efficiency Flame Seedless grapevines in both seasons.