This study was carried out during two successive growing seasons 2019 and 2020 on nine years old "Desert Red" peach trees (Prunus Persica L. Batsch) budded on Nemaguard rootstock. spaced at 4×4 m. trained to an open –vase system and grown in private orchard located at sedy Salem district, Kafrelsheikh Governorate. Subjected to Trees were horticulture practices usually, done in this region. The depth of water table is about 140-160 cm. the orchard soil is classified as clay. Egypt to study the effect of water shortage at different growth stages on some vegetative growth parameters, yield and fruit quality of " Desert Red " peach trees. The obtained data showed that, the highest mean values for studied vegetative growth parameters such as shoot length, shoot diameter, leaf area and specific leaf weight, yield (kg/tree – ton/fed.), and some fruit characters (fruit weight, fruit size, fruit length, fruit diameter and fruit shape) were recorded under control treatment (conventional irrigation). Meanwhile, vegetative growth parameters recorded the lowest values under T6 treatment, while the lowest values yield were recorded under T5. Fruit weight, fruit size, fruit length treatment, while the lowest values of yield were recorded under T5. Fruit weight, fruit size, fruit length and fruit diameter recorded the least values with T7 treatment. Concerning, productivity of irrigation water (PIW), whereas the highest values were obtained by T6 treatment, T5 treatment gave the lowest values. Fruit firmness, TSS and anthocyanin content in fruit peel of " Desert Red " peach trees were significantly affected by irrigation treatments, where, T7 treatment recorded the highest values for measured fruit firmness and TSS, while T6 treatment recorded the highest values for anthocyanin. The lowest values for measured fruit firmness, TSS and anthocyanin content were found under control condition (standard irrigation). Hence, we can recommend peach growers to apply T3 Treatment (10.186 m3/tree/year = 2678.92 m3/fed./year) to save 25%of irrigation water, as well as, to obtain about the same yield of control trees.