The growth and some metabolic activities of the five species namely Chlamydomonas reinhardtii (Dang), Chlorococcum humicola (Nag), Scenedesmus obliquus (Turp) Kütz(green algae) and Anabaena circinalis (Rabh.)and Wollea saccata (Wollea Bornet and Flahault) (Blue-green algae) isolated from soil at Assiut, Egypt were investigated under various concentrations of Cd²⁺, Ni²⁺ and Pb²⁺. The growth of the C. reinhardtii, C. humicola and S. obliquus were inhibited by all used heavy metals. The highest inhibitory effect was exerted by Ni²⁺ or Cd²⁺, while the lowest toxicity was exerted by Pb²⁺. However, the growth was enhanced by low and medium concentrations of Pb²⁺. The toxicity of heavy metals for C. reinhardtii, C. humicola, S. obliquus and W. saccata was as follows Ni²⁺ > Cd²⁺ > Pb²⁺. In case of A. circinalis the toxicity of heavy metal was as follows Cd²⁺ > Ni²⁺ > Pb²⁺. Soluble sugars, soluble protein, free amino acids and proline of all species, exhibited a high significant increase with all tested heavy metals supplemented. Insoluble carbohydrates, were generally lowered in various treatments, of heavy metals irrespective the test algae.