Quality of water in Egypt is determined by a periodic monitoring program where natural, chemical and microbiological indicators are measured. The River Nile monitoring points are examined periodically every four months. Monitoring the impact of various sources of drainage especially industrial drainage on waterways, as well as monitoring hot spots on the riverbanks can be a true criterion for judging quality of fresh water of the River Nile. Some parameters were measured, Water electrical conductivity, water temperature and ions concentration. Also, the study concluded that, turbidity degree, COD, Total Dissolved Solids (TDS), As for Total Dissolved Solids (TDS). Values of Nitrate concentrations showed that Nile water is of (excellent) quality. This also assures the validity of water for all uses. Most results through my researching years on the Nile water quality show the validity of that water for all uses. Comparing the criteria of water quality index (WQI) for the River Nile, and water quality of some different waterways in the world, was carried out.