Anaerobic digestion is a biochemical process used globally to convert the organic matter present in wastes into a process enhancing biogas production. Biogas production via anaerobic digestion (AD) of wastes is a very attractive, yet a challenging task. The slow rate of biodegradation and the presence of impurities in biogas expose the whole process to several risks. However, the addition of nanoparticles (NPs) can influence the performance and stability of the AD process . AD is a complex biochemical process which converts complex organic wastes into a gas mixture containing methane (CH4), carbon dioxide (CO2), water vapor, hydrogen sulfide (H2S), hydrogen, and ammonia. The sluggish rate of biodegradation of complex organic substrates, i.e., ligocellulosic substrates, limits the performance and efficiency of the AD process. Furthermore, because of hazardous components that may impair the efficiency of the AD process, such as organic matter and ammonia in wastewater and various organic , substrates may need pre-treatment such as thermal and acidic/alkaline. Nanotechnology a growing impact on a wide range of microbiological, pharmaceutical, and pure technological applications. The current application in production benefits from producing bioenergy from biomass is still highly limited. This work examines the effects of NPs additions on the AD. In addition, this research covers the benefits and the drawbacks of nanoparticles in producing of biogas.