The current study investigates the effectiveness of using Neuro Linguistic Programming on developing English oral communication skills of ESP learners. Participants involved in the present study were 60 freshmen college student (30 male and 30 female) who were enrolled in the Higher Institute of Engineering and Technology located at New Damietta City. They were assigned at random into two groups: experimental (n=30) and control (n=30). Both groups were taught by the same instructor.  However, the experimental group was taught via Neuro-Linguistic Programming.  Meanwhile, the control group received the regular type of instruction. Instruments used in this study included: (a) A questionnaire for determining the most important oral communication skills required by the targeted learners, and (b) an oral communication test that was used before and after implementing the suggested teaching strategy.  T-test results revealed that experimental group students' oral communication skills were significantly developed more than the control's as a result of using Neuro Linguistic Programming. It could be concluded that Neuro-Linguistic Programming is effective for enhancing English oral communication skills of ESP learners