Based on the spread of the phenomenon of indiscriminate drug use in Egypt - reaching the point of describing it as chaotic - in a way that has become causing many risks, some of which are medical and health, and some of which are economic. One of the role of education in raising the level of health awareness, through which it provides students and community members with information and experiences with the aim of influencing their knowledge, behavior and health tendencies, as well as their health and the health of their community in which they live so that they can enjoy a healthy life.The present paper discusses this phenomenon, its risks, and the role that pharmaceutical education can play in confronting it by addressing the following points: - Reviews intended by randomization of drug use and the most prominent manifestations of randomness? - Examine the causes of the random spread and chaos of drug use in Egyptian society, the dangers that could result from their spread, and the approaches to confronting them. - A review of what is meant by drug education, its goals and mechanisms, in overcoming randomness in drug use.- Recommendations and proposals for activating the role of drug education in facing the indiscriminate use of drugs in Egypt. Key words: medicine ; drug education ; random use of medicine.