This work presents –for the first time- the geomorphological characteristics of a recently explored karst cave (Al-Umrani karst cave) in eastern Egypt, allowing for better understanding of paleoclimate of Egypt in particular and the Sahara in general. This study provided a detailed geomorphological map and topographic profiles for the cave, which is located 12 km from the eastern bank of the Nile.  With a total area of 61 m², the cave extends over only 32 m, with a breadth of about 17 m and a depth of 14 m from the entrance to the deepest point.  Al-Umrani Cave is a classic karst cave created by groundwater near the western edge of the Eocene limestone of the Northern Plateau of the Eastern Desert. The cave was formed in a shallow marine limestone hill (Mokattam Group, Samalout Formation) of the Middle Eocene. Inside the cave several paleo-karst features were recognized such as stalactites, columns, and few stalagmites. These geomorphological features indicate that the area was a relatively humid tropical environment during the karistirization activities up to the Quaternary. The cave led to the opening of an entranceway to multi-stages steeply passage to the major double karst chambers, it is formed along a fault line through the limestone hill. In this study, we also assessed effects of the Quaternary fluvial terraces of Wadi Al-Amrani on the cave morphology. This assessment was made based on extensive field work, combined with employing geomorphic mapping, digital elevation model (DEM) analysis, hydro-morphological analysis of Wadi Al-Umrani basin and its network, and detailed surveying of the interior cave using a laser Total Station, in addition to a laboratory analysis of stalactites samples and ¹⁴C dating.