Background: Bariatric surgery proved to be the only successful treatment option leading to long-term weight loss with improvement of obesity related comorbidities. The Laparoscopic Sleeve Gastrectomy (LSG) is now one of the most popular bariatric procedure worldwide with rising prevalence over last decade, while the Mini Gastric Bypass (MGB) is now gaining some popularity as a relatively new bariatric procedure
Aim of the work: to evaluate the effect of two types of bariatric surgery; mini-gastric bypass and sleeve gastrectomy, on lipid profile and compare the results in both groups.
Patients and Methods: This study was carried out on sixty morbidly obese persons suffering dyslipidemia. This included 30 patients underwent mini-gastric bypass (Group1) and 30 patients underwent sleeve gastrectomy (Group2). Patients were evaluated preoperatively and 3 months postoperative regarding their anthropometric data (weight, height, and Body mass index) and total lipid profile (total cholesterol, HDL, LDL and triglycerides).
Results: Baseline preoperative anthropometric measures showed that no statistically significant difference between the two groups. Baseline pre-operative lipid profile measures showed no statistically significant difference between the two groups regarding total cholesterol and HDL levels while there was a significant difference in LDL and triglycerides levels.
It showed that LDL level of patients in (sleeve gastrectomy) group was significantly higher than LDL level of (mini gastric bypass) group (179.33 ± 28.98 mg/dl vs 157.86 ± 31.66 mg/dl respectively) (p value <0.05) while triglycerides level of patients in (mini gastric bypass) group was significantly higher than triglycerides level of (sleeve gastrectomy) group (222.50 ± 56.44 mg/dl vs 188.59 ± 28.92 mg/dl respectively) (p value <0.05).
Three months post-operative anthropometric measures showed that post-operative weight and BMI were significantly higher in mini gastric bypass group than sleeve gastrectomy group (108 ± 14.2 Kg vs 100.98 + 12.27 Kg and 42.85 ± 4.90 Kg/m2 vs 38.84 ± 4.39 Kg/m2 respectively) (p value <0.05). (Table 4, Figure 7 & 8)
Three months post-operative lipid profile showed no statistically significant difference between the two groups regarding total cholesterol and HDL levels while there was a significant difference in LDL and triglycerides levels  Comparing the two groups regarding amount of change in LDL. It shows that there was a statistically significant difference between pre and post-operative LDL in both groups (p value <0.05), there was a statistically significant difference between two groups regarding mean LDL (p value < 0.05) and there was a statistically significant difference between two groups regarding amount of change in LDL (p value <0.05).
Conclusion: According to our results both laparoscopic techniques; LSG and MGB were effective in achieving significant weight loss and improvement of obesity-associated medical comorbidities; dyslipidemia. Still LSG could be preferred in patients with dyslipidemia. The decrease of LDL, cholesterol and triglycerides being similar to MGB but a higher increase of HDL being documented.