Application servant leadership has become essential in hospitality establishments, because of changes and fluctuations faced by today's business environment. Which imposed many challenges to those establishments. This study was aimed at exploring the impact of servant leadership on reducing employees' occupational stressors relationship five-star hotels in Cairo. to achieve this, a questionnaire consisting of 31 phrases was designed. Data was gathered from 383 employees from some of five-star hotels in Cairo. results are showing that There are many hospitality organizations that value servant leadership. In the business world it is reported that Fortune-listed companies (2019), such as Marriott International Chain ranked thirty- first, Four Seasons Hotels ranked eighty-nine, apply servant leadership principles in their business operations. The results proved that servant leadership is high in five-star hotels in Cairo with mean (3.85). The results also indicate a low level of employees' occupational stressors relationship in five-star hotels in Cairo with a mean (1.93). The results reveal a statistically significant effect of servant leadership on reducing employees' occupational stressors relationship five-star hotels in Cairo.