Iodoform oxidation for drug ketone (spusforonion) at room temperature by using the conductivity study and spectrophotometric in basic medium. The conductivity study showed that molar conductance values were decreased with increasing of time at (2x10^-4-4x10^-4) concentration, while at ( 5x10^-4-6x10^-4) the value of molar conductance was increased, due to the reaction in presence of basic medium and apply the Helmy's theory of oxidation solutions was applied in ethanol for the initial infinity Molaric conductivity Ʌ_οat 25⁰  ̊was found the linear relationship between the lnɅ and C^1/2for the weak electrodes. The second study was spectrophotometric in a basic medium which showed that the reaction is related to the first order for the oxidation drug concentration by the iodoform.