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109752

Immunological study for Helicobacter pylori bacteria in Egyptian patients.

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Last updated: 25 Dec 2024

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Abstract

Helicobacter pylori (H. Pylori) are a helix shaped, microaerophilic, Gram-negative, flagellated bacteria. H. Pylori and mankind have an ancient relationship for at least 50,000 years. Commonly the first noninvasively testes used for H. pylori infection's detection were immunological tests like blood antibody test and stool antigen test. We investigated the more efficient susceptibility immunological test for detection of H.pylori infection in adult Egyptian patients by comparing the results of H. Pylori IgA (HpIgA), IgG in serum blood (HpIgG) and H.pylori Ag in stool (HpSAg) for 30 adult patient against control group using ELISA technique. The results showed that each test could be used successfully for diagnosis of H. pylori. Finally HpSAg showed reliable results with high sensitivity (> 95%) followed by HpIgG (87.5%), while HpIgA showed the lowest sensitivity (37.5%). Our findings confirms the use of the mentioned immunological tests for detecting them H. Pylori infection and suggest the use H. Pylori Ag in stool as the most economic, sensitive and reliable method alone or followed by IgG antibody test as confirmatory test to be the first choices for early diagnosis of H. Pylori especially in developing countries.

DOI

10.21608/jbaar.2016.109752

Keywords

Helicobacter pylori, immunological test, IgA, IgG, patients

Authors

First Name

MOHAMED H.

Last Name

YASSIN

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Affiliation

Botany Department, Faculty of Science Benha University, Benha, Egypt.

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First Name

TAGHREED A.

Last Name

ZIDAN

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Affiliation

Botany Department, Faculty of Science Benha University, Benha, Egypt.

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First Name

SAMUEL T.

Last Name

MELEK

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Affiliation

Parasitology and Blood Research Department, National Organization for Drug Control and Research (NODCAR), Cairo, Egypt.

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First Name

MOHAMED E.

Last Name

RASHED

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-

Affiliation

Microbiology Department, National organization for Research and Control of Biologicals (NORCB),Cairo, Egypt. , Botany Department, Faculty of Science Benha University, Benha, Egypt.

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Volume

2

Article Issue

12

Related Issue

16669

Issue Date

2016-12-01

Receive Date

2016-11-08

Publish Date

2016-12-22

Page Start

758

Page End

763

Print ISSN

2356-9174

Online ISSN

2356-9182

Article File

JBAAR_Volume 2_Issue 12_Pages 758-763.pdf

PDF . 427.4kB

Link

https://jbaar.journals.ekb.eg/article_109752.html

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https://jbaar.journals.ekb.eg/service?article_code=109752

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Original Article

Type Code

1,272

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Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

Immunological study for Helicobacter pylori bacteria in Egyptian patients.

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Article

Created At

22 Jan 2023