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109492

Effect of calcium ionophore A23187 on the sperm in intracytoplasmic sperm injection.

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Last updated: 25 Dec 2024

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Abstract

The present study evaluated the effect of calcium ionophore A23187 on sperm in intracytoplasmic sperm injection (ICSI) cycles using sperm from different sources. The 80 cycles evaluated were divided into four subgroups according to sperm quality and origin (normospermia- oligoathenoteratospermia–epidermal–testicular), subgroups were further split into experimental groups, depending on whether the spem treated or not treated with calcium ionophore. For each experimental subgroup, ICSI outcomes were compared between groups. In conclusion we found that using calcium ionophore increase the fertilization rate in case of sperm treatment with calcium ionophore before ICSI for oligoathenoteratospermia (OAT) & testicular subgroups, with enhancing embryos quality in testicular subgroup only

DOI

10.21608/jbaar.2016.109492

Keywords

Calcium ionophore A23187, Fertilization rate, embryos quality, ICSI

Authors

First Name

Abd El-Wahab

Last Name

El-Ghareeb

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Affiliation

Zoology Department, Faculty of Science, Cairo University, Egypt.

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First Name

Ibrahim Yahia

Last Name

Abd el-Kadr

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-

Affiliation

Zoology Department, Faculty of Science, Cairo University, Egypt.

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First Name

Amr Tharwat

Last Name

Al Ahwany

MiddleName

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Affiliation

Andrology Department, Faculty of Medicine, Cairo University, Egypt

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Orcid

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First Name

Aziza Mansour

Last Name

Ali

MiddleName

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Affiliation

Obstetrics & gynecology department, International Islamic center for population studies and research, Al-Azhar University

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Orcid

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First Name

Ola Ismail

Last Name

Hassan

MiddleName

-

Affiliation

Obstetrics & gynecology department, International Islamic center for population studies and research, Al-Azhar University

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Volume

2

Article Issue

10

Related Issue

16640

Issue Date

2016-10-01

Receive Date

2016-09-12

Publish Date

2016-10-22

Page Start

661

Page End

669

Print ISSN

2356-9174

Online ISSN

2356-9182

Article File

JBAAR_Volume 2_Issue 10_Pages 661-669.pdf

PDF . 589.3kB

Link

https://jbaar.journals.ekb.eg/article_109492.html

Detail API

https://jbaar.journals.ekb.eg/service?article_code=109492

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Original Article

Type Code

1,272

Publication Type

Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

Effect of calcium ionophore A23187 on the sperm in intracytoplasmic sperm injection.

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Article

Created At

22 Jan 2023