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106916

In vitro Effect of LC90 of albendazole and Allium sativum water extract on the fine structure of Capillaria sp. (Capillaridae Nematoda).

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Last updated: 04 Jan 2025

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Abstract

Fish parasites are of economic and health importance where they cause serious problems in commercial fish farms and it can be transferred to human and animals. Capillaria species are nematodes of serious fish diseases which may be transferred to human.The present study was conducted to detect the in vitro effect of sublethal concentration (LC90) of albendazole( ABZ ) and Allium sativum (garlic) cloves water extract on ultra structure of Capillaria sp. collected from fresh water catfishes, Bagrus docmac and B. bayad using SEM and TEM. The morality rates of the adult Capillaria sp. in vitro exposed to different concentrations of albendazole and Allium sativum water extract was recorded after 24 hours exposure time. A. sativum water extract had higher effect than albendazole where lower concentration of A. sativum extract (18 x103 ppm) gave maximum mortality rate (100%) , 24 hours post exposure. SEM studies of the cuticle of adult Capillaria sp. in vitro treated with LC90 (17.161 x103 ppm) of A. sativum water extract for 24 hours revealed that it induced severe changes in the cuticle integrity more than those treated with concentration LC90 (5.543 x 106 ppm) of albendazole. TEM studies revealed deformation of the cuticle, hypodermis, muscles and digestive system in worms treated with LC90 (17.161 x103 ppm) of Allium sativum water extract.

DOI

10.21608/jbaar.2016.106916

Keywords

Capillaria, Albendazole. In vitro, Allium sativum, SEM, TEM

Authors

First Name

Amal I.

Last Name

Khalil

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Affiliation

Zoology Department, Faculty of science, Tanta University, Tanta, Egypt

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First Name

Nahla A.

Last Name

Radwan

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Affiliation

Zoology Department, Faculty of science, Tanta University, Tanta, Egypt

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First Name

Gamalat Y.

Last Name

Osman

MiddleName

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Affiliation

Zoology Department, Faculty of science, Menoufia University, Menoufia, Egypt

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First Name

Alyaa M.

Last Name

Abo Msalam

MiddleName

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Affiliation

Zoology Department, Faculty of science, Menoufia University, Menoufia, Egypt

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Orcid

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First Name

Omaimah A. M.

Last Name

Maghrabi

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Affiliation

Biology Department, Faculty of science, Umm Al Qura University, Makkah, Saudi Arabia

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Volume

2

Article Issue

2

Related Issue

16119

Issue Date

2016-02-01

Receive Date

2016-01-20

Publish Date

2016-02-01

Page Start

125

Page End

135

Print ISSN

2356-9174

Online ISSN

2356-9182

Link

https://jbaar.journals.ekb.eg/article_106916.html

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https://jbaar.journals.ekb.eg/service?article_code=106916

Order

6

Type

Original Article

Type Code

1,272

Publication Type

Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

In vitro Effect of LC90 of albendazole and Allium sativum water extract on the fine structure of Capillaria sp. (Capillaridae Nematoda).

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Article

Created At

22 Jan 2023