Beta
106910

Ameliorating effect of propolis extract against equigan induced

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

-

Abstract

Equigan is an androgenic steroid that improves the growth and food conversion in meat producing animals. The present study was performed to determine the ameliorating effect of propolis in the toxicity of the rat testes induced with Equigan. Fourty male albino rat were divided into four groups (10 animals each); the control group includes animals that injected intramuscularly with olive oil. The second group includes rats received propolis. The third group is the experimental group included animals that received intramuscular injections of Equigan. The last group was co-administrated group where rats received Equigan along with propolis. The results suggest that misuse of growth promoter Equigan may contribute to continuous damage of the testicular function and structure that shown a significant increase in nitric oxide (NO), malondialdehyde (MDA), testosterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH) in Equigan group when compared to the control group, these results decrease in co-administrated Equigan with propolis. On the other hand a significant decrease in superoxide dismutase (SOD), catalase, Glutathione (GSH) and total thiol in Equigan group when compared with control group, and a significant increase in co-administrated Equigan with propolis. It was concluded that; propolis has ameliorating role on the biochemical alterations in Equigan induced testicular toxicity in male rat.

DOI

10.21608/jbaar.2016.106910

Keywords

Steroid hormones, Equigan, Propolis, testes, Oxidative Stress, antioxidants, Rats

Authors

First Name

Ahmed

Last Name

Massoud

MiddleName

-

Affiliation

Department of Home Economics, Faculty of Specific Education, KafrElShaikh University, Egypt

Email

-

City

-

Orcid

-

First Name

Ehab

Last Name

Tousson

MiddleName

-

Affiliation

Department of Home Economics, Faculty of Specific Education, KafrElShaikh University, Egypt

Email

toussonehab@yahoo.com

City

-

Orcid

-

First Name

Nahla

Last Name

Zedan

MiddleName

-

Affiliation

Department of Nutrition and Food Science, Faculty of Home Economics, University of Tabuk, Tabuk 71491, Saudi

Email

-

City

-

Orcid

-

First Name

Ali E.

Last Name

Abd elwahab

MiddleName

-

Affiliation

Department of Home Economics, Faculty of Specific Education, KafrElShaikh University, Egypt

Email

-

City

-

Orcid

-

Volume

2

Article Issue

2

Related Issue

16119

Issue Date

2016-02-01

Receive Date

2016-01-17

Publish Date

2016-02-01

Page Start

100

Page End

106

Print ISSN

2356-9174

Online ISSN

2356-9182

Link

https://jbaar.journals.ekb.eg/article_106910.html

Detail API

https://jbaar.journals.ekb.eg/service?article_code=106910

Order

3

Type

Original Article

Type Code

1,272

Publication Type

Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

Ameliorating effect of propolis extract against equigan induced

Details

Type

Article

Created At

22 Jan 2023