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106045

Histological and Biological Effects of Some Soft Drinks on Male Albino Rats

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Last updated: 25 Dec 2024

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Abstract

sodas that could have a caloric or noncaloric sweetener. Several studies showed that the excessive consumption of soft drinks leads to harmful health effects. This study aimed to determine the effects of some soft drinks on the public health by examining the histological structure of the kidney, body weight, biochemical values, bone mineral density (BMD ) and bone Xray. Twenty male rats, (weighing 140 ±5 g), were divided into 4 groups. ; Group 1 (the control group) fed only on basal diet. ; Group 2 received a cola diet soft drink; Group 3 received an orange soft drink and Group 4 received a lemon soda soft drink. For histopathological examination, The kidneys were removed. The bone mineral density of the rats was assessed using Dual-energy X-ray absorptiometry (DXA). The body weight change and blood values were also determined. The histological examination of the kidneys showed general glomerular congestion, vacuolation, intertubular bleeding, tubular necrosis and hypotrophy of glomeruli. The weight gain was higher in the groups consuming diet drinks than the control group and the other group rats. There was a significant decrease in the bone mineral density of test groups when compared to the control group.

DOI

10.21608/jbaar.2015.106045

Keywords

bone, DXA, histopathology, kidneys, Soft Drinks

Authors

First Name

Nehad R.

Last Name

EL-Tahan

MiddleName

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Affiliation

Nutrition & Food Science Dept., Faculty of Home Economics, Minoufia University, Shebin EL-Kom

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First Name

Rania A.

Last Name

Ahmed

MiddleName

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Affiliation

Zoology Department, Faculty of Science, Suez University, Suez, Egypt

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Volume

1

Article Issue

6

Related Issue

16046

Issue Date

2015-12-01

Receive Date

2015-11-22

Publish Date

2015-12-01

Page Start

342

Page End

349

Print ISSN

2356-9174

Online ISSN

2356-9182

Article File

JBAAR_Volume 1_Issue 6_Pages 342-349.pdf

PDF . 295.5kB

Link

https://jbaar.journals.ekb.eg/article_106045.html

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https://jbaar.journals.ekb.eg/service?article_code=106045

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12

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Original Article

Type Code

1,272

Publication Type

Journal

Publication Title

Journal of Bioscience and Applied Research

Publication Link

https://jbaar.journals.ekb.eg/

MainTitle

Histological and Biological Effects of Some Soft Drinks on Male Albino Rats

Details

Type

Article

Created At

22 Jan 2023