Objective:The present study aims to investigate the possible adverse effects of the subcutaneous injection of nitroxynil and oral administration of albendazole in rabbits.
Design:Randomized controlled experimental study.
Animals: 18 New Zealand rabbits of 1.50 ± 0.5 kg body weight, were allocated randomly into three groups (n=6).
Procedures: Group A served as control, the group B was treated with albendazole (20 mg /kg B. wt.) orally and the group C was treated with nitroxynil (10mg /kg B. wt.) subcutaneously. Blood samples were collected at 1^st, 7^th and 14^th days post drugs administration for hematological and biochemical determination. In addition, histopathological examination of liver, kidney and intestine specimens were performed.
Results:The obtained results evoked a significant decrease in RBCs, PCV, Hb, WBCs, lymphocytes , neutrophils, GSH and catalase values in group B and C compared with that group A.  On the other hand, group B and C elevated serum ALT, AST, urea, creatinine, and MDA significantly (P ≤0.05) compared with group A