Proliferative enteropathy (PE) is a recently described disease of horses that is char acterized by signs of elevated body temperature, weight loss, diarrhea and death. The disease is caused by Lawsonia intracellularis. n-eatment may include jlunixin meglu mine,dexamethasone and prednisone to control inflammation. In addition antiulcer drugs such as cimetidine may be required. Finally, antibiotic therapy such as oral ad ministration of combined erythromycin/rifampin, or chloramphenicaol and oxytetracy cline should be initiated.When PE was described in horses for the first time, Campylobacter spp was thought to be the causative agent (Duhamel and. Wheel don 1982). However when the second equine case was reported, the causative agent, Law sonia intracellularis, has been well character ized in pigs