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185587

Pharmacological Studies on Marbofloxacin on Diarrheic Calves

Article

Last updated: 22 Jan 2023

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Subjects

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Tags

Pharmacology and toxicology

Abstract

One –hundred diarrheic calves were used to differentiate various reasons for calf diarrhea by using rapid diagnostic kits which found the main causative agents for diarrhea occurrence are corona virus (28%), Rota virus (25%), Cryptosporidium (24%) and E. coli (23%), Respectively, in addition to study concurrent use of marbofloxacin (a third generation member of quinolone) in treatment of diarrheic calves infected with E. coli. Then twenty Holstein calves (0-10 days old) in special dairy farm at Damietta Governorate were isolated and divided into two groups, each group contain ten animals. First group was kept as control without any drug. The second group include ten diarrheic calves infected with E-coli and was injected by marbofloxacin intramuscularly (2mg/kg B. W) for 3 successive days. Results revealed a significant increase in total leukocytic count, lymphocyte count, monocyte count, eosinophil count, globulin, ALT, AST, ALP, creatinine and urea level. On other hand results recorded a significant decrease in total erythrocytic count, hemoglobin content, PCV, MCH, MCHC, total protein, Albumin and thrombocyte count in marbofloxacin treated group compared to control one.

DOI

10.21608/mvmj.2019.01.106

Keywords

Marbofloxacin, calves, diarrhea

Authors

First Name

Mohamed

Last Name

El-sayed

MiddleName

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Affiliation

Department of pharmacology Faculty of Vet. Med, Mansoura University.Egypt

Email

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City

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Orcid

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First Name

Rasha

Last Name

El- taysh

MiddleName

-

Affiliation

Department of pharmacology Faculty of Vet. Med, Mansoura University.Egypt

Email

-

City

-

Orcid

-

First Name

Ayat

Last Name

Abd el-Rahman

MiddleName

-

Affiliation

-

Email

-

City

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Orcid

-

Volume

20

Article Issue

1

Related Issue

22626

Issue Date

2019-03-01

Receive Date

2019-01-09

Publish Date

2019-03-01

Page Start

6

Page End

13

Print ISSN

1110-7219

Online ISSN

2682-2512

Article File

MVMJ_Volume 20_Issue 1_Pages 6-13.pdf

PDF . 681.0kB

Link

https://mvmj.journals.ekb.eg/article_185587.html

Detail API

https://mvmj.journals.ekb.eg/service?article_code=185587

Order

18

Type

Original Articles

Type Code

1,268

Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

MainTitle

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Details

Type

Article

Created At

22 Jan 2023