99 samples were collected from apparently healthy cows (20) and(35) cows suffering from various degrees of endometritis in dairy farms at Damieta and Dakahlia Governorate as well as(44) cows at Mansoura abattoir. The isolated bacteria from healthy cows were E. coli (20%), (13.3%) for S. aureus and K. oxytoca, (10%) for each of P. mirabilis, M. nishinomiyoensis and S. epidermidis, (6.7%) for each of P. rettegri and C. freundii and 3.3% for P. vulgaris, E. faecalis and P. aeruginosa, For endometritis cases, E. coli represented 34.8 % followed by S. aureus (19.3 %), (8.3 %) S. pyogenes, (5.5%) A. bovis, (4.6 %) for each of K. oxytoca and C. freundii, (4.5%) P. aeruginosa, (3.7%) for E. agglomerans and Salmonellae, (2.8%)A . pyogenes, (2.6%) Y. pseudotuberculosis, (1.8%) for K. pneumoniae and P. vulgaris and 0.9% for P. mirabilis and E. faecalis. Sensitivity of the most prevalent bacteria recovered from endometritis revealed that they were highly sensitive to enrofloxacin (97.41%), gentamicin (87.01 %), chloramphenicol (83.12%), norofloxacin (81.82%) and pipracillin (81.82%). Also, they were sensitive to ciprofloxacin (75.32%), flumox (63.64%), amikacin (58.44%), neomycin (62.33%), nitrofurantion (58.44%), cefoperazone (62.33%), cefotaxime (58.44%), docxycycline (55.84%), erythromycin (54.54%) and flumequine (53.24%) but they were highly resistant to pencillin G (11.68%), streptomycin (38.96%), ampicillin (33.76%), SXT (41.56%), oxytetracycline (37.66%) and lincospectinomycin (46.75%).