Efficacy of Fosbac plus T for control of pasteurella anatipestifer in peking ducking was evaluated by disc diffusion methods where P anatipestifer strain were highly sensitive to this drug in this study fosbac plus T was given with drinking water at a dose of 160mg / kg B wt for three successive days in naturally infected ducks with P anatipestifer the durg at this dose reduced mortality from 25% to 5% it improved the adverse effect of P anatipestifer on hematological parameters as evidenced by improvement of hypochromic macrocytic anaemia present in infected birds .Also it improved the liver functions as evidenced by the decrease in serum levels SAST SALT and serum globulin meanwhile the albumin level was increased compared with the infected group there was improvement of the kidney function of infected bird (7 days post treatment ) evidenced by decreased levels of serum creatinine uric acid and inorganic phosphorous with increased calcium levels compared with the infected group the histopathological examination of the liver and kidneys confirmed these results it is concluded that fosbac plus T is an effective and safe anatibacterial drug for treatment of pasteurellosis in pekin ducks moreover it has no adverse effects when given to normal ducks.