Detomidine hydrochloride (Domosedan) was administered intravenously t.o three groups of camels, using three different doses (25, 50 or 75pg/kg b.wi.). The levels of sedation and analgesia were graded and recorded. Sedation and analgesia were dose dependent. Detomidine at a dose rate of 75pgI kg produced profound sedation and analgesia. Significant hyperglycemia and bradycardia were r:ecorded after adminislra • lion of det.omidine and t.ill l.he recovery. No significant changes in hemoglobin concen• tration (Hb%}, PCV% , WBCs and RBCs counts, and blood creatinine or blood urea nitro• g en levels were recorded in all of the tested doses. Drugs for sedation and tranquilization are very useful in camel husbandry . medicine and sur gery. Deep sedation as well as analgesia is a mandatory for dealing with camels either tor some routine examinations or many surgical interventions. Several anesthetics . tranquilizers and an algesics have been used in camels (Fouad and Morcos, 1965; Khamis et al, 1973; Peshin et al, 1980, Sharma et al, 1983, El-Amrousi et al, 1986, White et al, 1986 and Fahmy et al, 1995). Chlorpromazine hydrochloride , propyonil promazine and acepromazine have been early evaluated as sedatives in camels (Said 1972, Khamis et al, 1973, Ali et al, 1989). Despite the advances in the field of tranquilizers and their uses in domestic animals, experience with their application on the camel have been still lacking until recent years (Fouad, 2000).