anorexia, loss of body weight, despression, recumbency alopecia and diarrhea. Estimation of serum minerals revealed increase in calcium, phosphorus and zinc concentration, as well as decreased levels of magnesium, sodium and potassium in serum while those of copper and iron were in the normal physiological value. Examination of ration samples revealed decrease in protein content and increase in calcium, phosphorus, and iron levels. While, magnesium, copper and zinc levels were adequate to cover requirement of calves. Also, acid number was high indicated oxidative rancidity of the ration.The mineral imbalance state of ration in addition to rancidity were suggested to be the real cause of the problem as the symptoms were subsided when the ration was replaced by a new one. ,