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119923

Cytogenetic effects of phoxim (A – new organophosphorous insecticide) 0n bone marrow cells of rats

Article

Last updated: 22 Jan 2023

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Tags

Pharmacology and toxicology

Abstract

The present study was designed to investigate the possible mytagenic influence if any of phoxun (1.5 and 1.10 LD50) in 32 immature male rats. The abtained daia revealed that the mutagenic effect of phoxim showed dose response relationship. The main types of structurual aberrations in ireated rais were breaks, gups, fragments and delation. No numerical aberrations were noticed during the examination of the bone marrow melaplase cells of trcatcd rais with 1/5 or 1/10 LD50 of phoxin. Moreover,phoxin induced a significant increase in the percentage of micronucleated polychromatic and normochromalic cells of treated rats.

DOI

10.21608/mvmj.2000.119923

Authors

First Name

M

Last Name

Amer

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

O

Last Name

Gad

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

K

Last Name

El-Hady

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

E

Last Name

El-khatib

MiddleName

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Affiliation

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Email

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City

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Orcid

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Volume

2

Article Issue

2

Related Issue

17831

Issue Date

2000-12-01

Receive Date

2000-07-02

Publish Date

2000-12-01

Page Start

63

Page End

73

Print ISSN

1110-7219

Online ISSN

2682-2512

Link

https://mvmj.journals.ekb.eg/article_119923.html

Detail API

https://mvmj.journals.ekb.eg/service?article_code=119923

Order

1

Type

Original Articles

Type Code

1,268

Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

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Details

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Article

Created At

22 Jan 2023