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127612

GENOTOXICITY OF BISPYRIBAC SODIUM IN ALBINO RATS

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Pharmacology and toxicology

Abstract


Genotoxicity of pesticides constitute great concern that affect population health, commercial formulation of such pesticides may increase the genotoxicity of certain pesticides, the genotoxic effect of bispyribac sodium had been studied in albino rats given orally 65.88, 32.94 and 16.47 mg / kg of bispyribac sodium twice per week for 3 months and the results indicated that significant increase in chromosomal aberration (break, fragment, gap, ring and chromosomal association) in respect to control which was dose dependent also significant increase in DNA quantity, also there was significant increase in micronuclei level in respect to control and decrease in mitotic activity in bone marrow cell where the mitotic index had decreased drastically in response to control value and these results confirm that bispyribac sodium may have genotoxic effect affect in albino rats.

DOI

10.21608/mvmj.2017.127612

Keywords

bispyribac sodium, Rats, toxicity

Authors

First Name

Fathy

Last Name

Sleem

MiddleName

R

Affiliation

prof. dr. of forensic medicine and toxicology Faculty of veterinary medicine, Mansoura University, Egypt.

Email

-

City

-

Orcid

-

First Name

Mahmoud

Last Name

Elalfy

MiddleName

M.

Affiliation

Lecturer of forensic medicine and toxicology Faculty of veterinary medicine, Mansoura University, Egypt.

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Abou-mosallam

MiddleName

S.

Affiliation

Demonstrator of forensic medicine and toxicology Faculty of veterinary medicine, Mansoura University, Egypt. Faculty of veterinary medicine, Mansoura University, Egypt

Email

-

City

-

Orcid

-

Volume

18

Article Issue

1

Related Issue

17809

Issue Date

2017-06-01

Receive Date

2017-09-12

Publish Date

2017-12-12

Page Start

491

Page End

502

Print ISSN

1110-7219

Online ISSN

2682-2512

Article File

MVMJ_Volume 18_Issue 1_Pages 491-502.pdf

PDF . 543.0kB

Link

https://mvmj.journals.ekb.eg/article_127612.html

Detail API

https://mvmj.journals.ekb.eg/service?article_code=127612

Order

33

Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023