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127395

IMMUNOLOGICAL STUDIES ON E.COLI VACCINE IN CHICKEN

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Bacteriology

Abstract

The present study was carried out on One hundred and fifity , one day old chicks to evaluate the immunogenicity of multivalent pilus vaccine containing pili from the three common pathogenic serotypes of E. coli (O1, O2 and O78). Nienty vaccinated birds at 14 days & 28 days of age by 0.5ml s/c of pilus vaccine at base of neck and 60 unvaccinated were divided to 4 subgroups (30 vaccinated & 20 unvaccinated) were used for challenge two weeks after second dose . Each group was challenged each with one type of E.coli strains O1 , O2 and O78. Blood samples were collected during the experiment from the flocks one week before vaccination and weekly for 7th week after the first dose of vaccination for evaluation of immune response by using ELISA test. The prepared multivalent E.coil pilivaccine from combination of O1, O2 and O78E.coli strains were seemed to cover good range of protection and has been elicited a protective immune response against virulent E.coli challenge with homologous and heterologous strains. strong correlation was found between antibody response vaccinated groups and low lesions score that indicated a good protection.

DOI

10.21608/mvmj.2017.127395

Keywords

chicken, E.coli, vaccine

Authors

First Name

Amany

Last Name

Abd.ELEmoaty

MiddleName

M

Affiliation

Dep. of Bacteriology, Mycology and Immunology, Fac. Vet.Med, Mans. Univ.

Email

-

City

-

Orcid

-

First Name

Ahmad

Last Name

Ammar

MiddleName

M.A

Affiliation

Dep. of Microbiology, Fac. Vet. Med, Zagazig Univ.

Email

-

City

-

Orcid

-

First Name

AlaaEldin

Last Name

Moustafa

MiddleName

H

Affiliation

Dep. of Bacteriology, Mycology and Immunology, Fac. of Vet. Med. KafrElsheikh Univ.

Email

-

City

-

Orcid

-

First Name

Ibrahim

Last Name

Ibrahim

MiddleName

S

Affiliation

Vaccines Research Institute,Abbasia,Cario

Email

-

City

-

Orcid

-

Volume

18

Article Issue

1

Related Issue

17809

Issue Date

2017-06-01

Receive Date

2017-09-12

Publish Date

2017-12-12

Page Start

549

Page End

558

Print ISSN

1110-7219

Online ISSN

2682-2512

Article File

MVMJ_Volume 18_Issue 1_Pages 549-558.pdf

PDF . 699.9kB

Link

https://mvmj.journals.ekb.eg/article_127395.html

Detail API

https://mvmj.journals.ekb.eg/service?article_code=127395

Order

29

Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

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Article

Created At

22 Jan 2023