EFFECTS OF MELATONIN ON TESTICULAR AND PITUITARY GLAND FUNCTIONS IN RATS - Egyptian Knowledge Bank

127347

EFFECTS OF MELATONIN ON TESTICULAR AND PITUITARY GLAND FUNCTIONS IN RATS

Article

Last updated: 04 Jan 2025

Subjects

Abstract

The present investigation was desgined to evaluate the effects of melatonin on testosterone and pituitary hormones levels in mature male rats Twenty mature male rats were used in this study. Animal were divided into two groups each one consists of ten rats . The first group considers as contral group administrated soya oil (2ml / kg) , the second group treated with melatonin (0.5mg 1 kg) for one month . After the end of the experiment rats were sacrificed and blood was collected into heparinzed tubes to separate plasma and testicular tissue were collected to detect oxidive changes of the malenaldehyde (MDA) concentration and activities of superoxide dismutase (SOD) and catalase (CAT) . The results revealed that plasma level of testosterone and luteinzing hormones were significantly deceases (P ‹ 0.5) in melatonin treated group as compared with normal one , while reduces testicular concentration of MDA and increases the SOD and catalase activities . It was concluded that Melatonin has direct effects on testiculars and pituitary gland hormones and has antioxidant effects.

DOI

10.21608/mvmj.2017.127347

Keywords

Melatonin, testis, Rats

Authors

View Authors

First Name

Nabil

Last Name

Abu Heakal

MiddleName

Affiliation

Department of physiology, faculty of veterinary medicine , Mansoura University

Email

City

Orcid

Volume

Article Issue

Related Issue

17809

Issue Date

2017-06-01

Receive Date

2017-09-12

Publish Date

2017-12-12

Page Start

593

Page End

594

Print ISSN

1110-7219

Online ISSN

2682-2512

Article File

MVMJ_Volume 18_Issue 1_Pages 593-594.pdf

PDF . 341.7kB

Link

https://mvmj.journals.ekb.eg/article_127347.html

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https://mvmj.journals.ekb.eg/service?article_code=127347

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Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

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