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126430

HEPATO-RENAL ALTERATIONS IN DAIRY CATTLE WITH SUBCLINICAL KETOSIS DURING TRANSITION PERIOD

Article

Last updated: 22 Jan 2023

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Tags

Internal Medicine and Infectious Diseases

Abstract

The purpose of the present study was to evaluate hepatic and renal functions in dairy cows suffered from sub clinical ketosis during the transition period. For this purpose, 730 Holstein Friesian dairy cattle, from a commercial dairy farm were included in this investigation. On the farm, only twenty four cows were located at a late gestation period. Blood samples were collected from each of the transition cows to estimate serum levels of β-hydroxy butyric acid (BHBA).Cows with no remarkable clinical signs but having serum BHBA> 1.20 mmol/L to 2.9 mmol/L were considered to have SCK (n = 20), while cows with no clinical signs and serum BHB < 1.00 mmol/L were considered controls (n = 4).Blood samples were then used to estimate serum values of alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen , and creatinine, total protein, albumin and globulin. Our findings demonstrated significant higher values of BHBA (P<0.05), blood urea (P = 0.019), AST (P = 0.021), and ALT (P = 0.001) in diseased cows than those in controls; while creatinine, total protein and globulin showed no significant changes. We conclude that cows with SCK demonstrated marked hepatic dysfunction with substantial evidences of fatty liver. Further studies are needed to evaluate the glomerulus filtration rate in the diseased cattle that have normal serum creatinine concentrations and suspected kidney disease.

DOI

10.21608/mvmj.2017.126430

Keywords

Sub clinical ketosis, dairy cattle, hepatic, renal function

Authors

First Name

Mohamed

Last Name

Youssef

MiddleName

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Affiliation

Department of Internal Medicine, Infectious Diseases and Fish Diseases, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt

Email

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City

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Orcid

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First Name

Maged

Last Name

El-Ashker

MiddleName

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Affiliation

Department of Internal Medicine, Infectious Diseases and Fish Diseases, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt

Email

-

City

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Orcid

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First Name

Marwa

Last Name

Younis

MiddleName

-

Affiliation

Department of Internal Medicine, Infectious Diseases and Fish Diseases, Faculty of Veterinary Medicine Mansoura University, Mansoura 35516, Egypt

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City

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Orcid

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Volume

18

Article Issue

1

Related Issue

17809

Issue Date

2017-06-01

Receive Date

2017-11-12

Publish Date

2017-12-12

Page Start

155

Page End

163

Print ISSN

1110-7219

Online ISSN

2682-2512

Article File

MVMJ_Volume 18_Issue 1_Pages 155-163.pdf

PDF . 597.2kB

Link

https://mvmj.journals.ekb.eg/article_126430.html

Detail API

https://mvmj.journals.ekb.eg/service?article_code=126430

Order

9

Publication Type

Journal

Publication Title

Mansoura Veterinary Medical Journal

Publication Link

https://mvmj.journals.ekb.eg/

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Article

Created At

22 Jan 2023