Beta
248308

The Effect of Some Beverage Rich in Chlorogenic acid on Rats suffering from Chronic Liver Damage Induced by Carbon Tetrachloride

Article

Last updated: 25 Dec 2024

Subjects

-

Tags

الإقتصاد المنزلى

Abstract

Chronic liver disease refers to on-going inflammation in the liver for at least 6 months with the potential to progress to cirrhosis and end-stage liver disease. In the present study, the effect of some beverage rich in chlorogenic acid on rats suffering from chronic liver induced by carbon tetrachloride (CCl4) was studied in Male albino rats. Forty-two rats were divided into six groups. Group 1: negative control group (normal, fed on basal diet), Group2: positive group, injected with CCl4 (fed on basal diet). Groups 3, 4, 5 and 6 were injected with CCl4 co-administered with green coffee, roasted coffee, green tea and black tea. The results showed that the administration of CCl4 resulted in significant increase in liver enzyme, in addition, CCl4 disturbed liver histology. There was a statistically significant difference between the positive control group when compared to green coffee and green tea groups (192.33 ± 6.83 g vs. 193.67 ± 7.50 g, respectively) in the final weight. Beverage extract has a beneficial effect on serum glucose, lipid profile, kidney, and liver function. Histopathological examination indicated that groups administered with green tea, roasted coffee have normal histological structure.

DOI

10.21608/ejos.2022.248308

Keywords

Chronic liver disease (CLD), carbon tetrachloride (CCl4), Chlorogenic acid (CGA)

Authors

First Name

ءالاء طارق

Last Name

حسنى

MiddleName

-

Affiliation

کلية التربية النوعيه

Email

dr.alaa.tarek@sedu.asu.edu.eg

City

القليوبية

Orcid

-

Volume

10

Article Issue

35

Related Issue

35498

Issue Date

2022-07-01

Receive Date

2021-10-22

Publish Date

2022-07-01

Page Start

29

Page End

54

Print ISSN

1687-6164

Online ISSN

2682-4353

Link

https://ejos.journals.ekb.eg/article_248308.html

Detail API

https://ejos.journals.ekb.eg/service?article_code=248308

Order

11

Type

المقالة الأصلية

Type Code

1,258

Publication Type

Journal

Publication Title

المجلة المصرية للدراسات المتخصصة

Publication Link

https://ejos.journals.ekb.eg/

MainTitle

The Effect of Some Beverage Rich in Chlorogenic acid on Rats suffering from Chronic Liver Damage Induced by Carbon Tetrachloride

Details

Type

Article

Created At

22 Jan 2023