Nowadays, different attitudes and new theories are emerging concerning teaching and learning, to improve the current models of education and broaden their horizons. Former studies have proven that human intelligence can reach its highest potential when holistic learning methods are applied. The purpose of this study is to manifest the intense relationship between science and art and to publish the advances made in science in the context of multidisciplinary learning. The review of the three research programs, the zero project of Harvard University, the Association for the Advancement of Art Education in the United States, and the report of the National Foundation for Education Research of the United Kingdom concluded that an integrative curriculum of art and science provides a solid foundation for teaching and learning, and it enhances the goodness of life. The incorporation of artistic disciplines to scientific education in primary and secondary schools strengthen academic performance, facilitate learning, and make teaching more enjoyable. Also, its value can be noticed in career opportunities since it develops the ability to acquire responsible behavior that is attentive to values in a social and ethical context. Such an approach in education teaches students to think in a global and multidimensional way, instead of retaining a large amount of information.