Laboratory and greenhouse experiments were conducted in El-Kassassin Res. Station, Ismailia, Egypt, in 2010/2011, to determine the effects of water salinity on linear growth of Pyrenochaeta terrestris, incidence of pink root and yield of garlic, as well as, the plant responses to the water salinity. Pyrenochaeta terrestris tolerates a high salinity level (35 mM NaCl) in culture. Irrigation with saline water increased pink root incidence in garlic inoculated with P. terrestris but yield was decreased. Irrigation of garlic until 20 mM NaCl did not inhibit plant growth development, but partial inhibition was observed at 25 mM NaCl level of garlic uninoculated with P. terrestris. Pink root increases by saline water are associated with the effect on plant response.