Abstract: The current research aimed to identify the effectiveness of a program in electronic stories based on one of the applications of artificial intelligence in developing psychological adaptation in autistic children, and to verify the extent to which the impact of this program remains for this group of children., The basic research sample consisted of (6) autistic children aged (4: 8) who frequented the communication unit at the Faculty of Medicine, Minya University during the year 2021/2022 AD, and the research applied a measure of psychological adaptation (photograph) for autistic children (prepared by researchers). The (CARS 2) scale for diagnosing autism, and a program in electronic stories based on the applications of artificial intelligence to develop psychological adaptation in autistic children (prepared by researchers), The results of the research indicated the effectiveness of electronic stories using artificial intelligence applications in developing psychological adaptation for autistic children. Learning in kindergarten and centers for people with special needs to enrich the children's educational and learning environment.