This study aims to investigate and deliberates the relationship between Organizational Learning Mechanisms, strategic agility, and organizational excellence in Employees of Kafrelsheikh University. Moreover, it examined the effect of strategic agility as a moderator of this relationship between Organizational Learning Mechanisms and organizational excellence. A total of 325 questionnaires were collected from respondents who were chosen from a stratified random sampling. The findings indicate that Organizational Learning Mechanisms and its dimensions, Knowledge recognition mechanisms, Knowledge assimilation mechanisms, and Knowledge exploitation mechanisms have a significant impact on strategic agility as well as organizational excellence. Moreover, the results indicate that strategic agility partial mediates the relationship between Organizational Learning Mechanisms and organizational excellence. The findings of this study can have significant implications for Employees of Kafrelsheikh University. The study observes that there is a critical shortage of Strategic Agility, Organizational Learning Mechanisms and that a greater understanding of the factors that influence the Organizational Excellence is needed, Therefore, Organizational Learning Mechanisms can lead to Organizational Excellence and Strategic Agility.